Gong Chen Lab @ Nankai / 南开大学陈弓课题组

恭喜博士生牟学清的研究成果被Organic Letter接收


恭喜博士生牟学清的研究成果被Organic Letter接收

Copper(I)-Catalyzed Enantioselective Intramolecular Aminotrifluoromethylation of O-Homoallyl Benzimidates

  • Xue-Qing Mou

  • , Feng-Ming Rong,

  • Heng Zhang

  • , Gong, Chen,* and Gang He*

Abstract

In the present paper, the Cu(I)-catalyzed intramolecular aminotrifluoromethylation of O-homoallyl benzimidates with Togni reagent I was reported. O-Homoallyl benzimidates equipped with terminal alkenes produced chiral 1,3-oxazines with high enantioselectivity in the presence of a chiral BOX ligand, and racemic tetrahydro-1,3-oxazepines were obtained in high yields from internal alkene derivatives with a monoprotected amino acid additive under similar conditions.



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Article classification: 新闻资讯
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